8:e5077710.7554/eLife.50777 Elife Summary Keywords glutathione peroxidase 1, spiral ganglion neuron, peroxynitrite, oxidative stress, nuclear factor-kappa B, hearing loss Citation Wang X, Han Y, Chen F, Wang M, Xiao Y, Wang H, Xu L and Liu W (2022) Glutathione Peroxidase 1 Protects Against Peroxynitrite-Induced Spiral Ganglion Neuron Damage Through Attenuating NF-B Pathway Activation
How to Prevent Muscle Loss While Using GLP-1s This is one of the biggest concerns I hear from women: "Will I lose muscle on a GLP-1?" The short answer: you might, unless you're intentional
Mitigate Potential Downsides: A compound that helps manage or offset a potential negative feedback loop or side effect of the primary agent
These may include diabetes, metabolic syndrome, or thyroid disease
Finally, personalized medicine approaches should be explored, taking into account genetic backgrounds (e.g., LRRK2 and SNCA mutations) and environmental exposures that influence iron metabolism and susceptibility to ferroptosis